TubeSpin® Bioreactor

TPP TubeSpin® Bioreactors have proven their advantages in large scale screening and optimizing of suspension cell system process development. The important parameters for the production upscaling can be evaluated with small amounts maximizing the number of parallel experiments at the same time. This lowers the costs and increases the efficiency of the process.

International design patent: The innovative design of the TubeSpin® Bioreactor 87600 was registered with the World Intellectual Property Organization (OMPI) in 2023!

Features of the TubeSpin® Bioreactors

  • TubeSpin® Bioreactor 15: working volume 1–15 ml
    • conical or round bottom
    • filter cap

  • TubeSpin® Bioreactor 50: working volume 1–35 ml
    • conical or round bottom
    • filter cap

  • TubeSpin® Bioreactor 450:  working volume up to approx. 300 ml 
    • conical bottom
    • filter cap
    • additional replacement cap available: “solid” #87355, “filter” #87356

  • TubeSpin® Bioreactor 600:  working volume up to approx. 400 ml
    • conical bottom
    • filter cap
    • additional replacement cap available: “solid” #87355, “filter” #87356
    • International design patent: The innovative design of the TubeSpin® Bioreactor 87600 was registered with the World Intellectual Property Organization (OMPI) in 2023
  • Filter cap with partly 5 different openings (A, B, C, D, E) or 10 equal openings
  • Fit standard centrifuge apparatus
  • Spin: 15'500 x g or 3'500 x g
  • Matching adapter plates for shakers for cultivation of suspension cells available
Racks and screw caps for bioreactors:
  • Replacement screw caps for large bioreactors
  • Rack for bioreactor 450/600 ml
  • Rack for bioreactor 15/50 ml
  • TPP adapter trays for shakers from Kuhner or Infors available
 

Recommendations for spin, throw and shaking speed can be downloaded here.

Good to know!

Recommendation

Orbital throw and rotational speed are important factors for the success. Pay also attention to the maximal weight with which the shaker can be loaded.


 

 

From swirling of wine to bioreactors - the essence of orbital shaking

An interesting film from scientists at EPFL that have managed to model the shape of the wave created in a glass of wine while swirling it. They figured out that given parameters allow reproducing the exact wave form, whatever the size of the recipient. These finding are useful to better calibrate orbital shaking bioreactors for cell culture. See original scientific footage (source: youTube).

 

Water loss

  • If small culture volumes are incubated over a longer period of time, the loss of water influences the growth of cells.
  • By the closure of one or several openings above the gas permeable and sterile PTFE membrane, this water loss can be minimized.

Steril gas exchange is guaranteed through the 0.22 µm pore size PTFE filter membrane.

Downloads

Shaker Information

Information on Centrifuges for Bioreactors

This information has been verified by the manufacturers of the centrifuges and provided to TPP. TPP assumes no liability for the correctness and completeness of the data. If you have any questions, please be sure to contact the technical service of the respective manufacturers or your local distributor

 

TypeProduct No.VersionVolume (ml)Dimensions
(mm)
MaterialMax
g Force
Qty / BagQty / CaseCase
(kg)
87015 15 ml, conical, filter cap 15 17.1 x 120 PP 15500 40 800 7.1
87017 15 ml, round, filter cap 15 17.1 x 120 PP 15500 40 800 7.1
87050 50 ml, conical, filter cap 50 30 x 115 PP 15500 20 180 3.1
87056 50 ml, round, filter cap 50 30 x 115 PP 15000 20 180 3.1
87450 450 ml, conical, filter cap 450 96 x 145 PP 3500 1 32 3.0
87600 600 ml, conical, filter cap 600 98 x 183 PP 3500 1 26 3.5
99013 Rack for 87600 3 x 87600 366 x 146 x 70 PP 1 6 2.4
99017 Rack for 15 / 50 ml tube 18 x 15 ml / 10 x 50 ml 209 x 98 x 62 PP 1 45 5.1
87355 screw cap "solid" 450/600 70 x 21 PE -- 1 36
87356 screw cap "filter" 450/600 70 x 21 PE -- 1 36
--- TPP Shaker Tray --- --- --- --- ---
87414 Kuhner tray 162/50 162 x 50 ml 800 x 420 Alu 1 1 12
87411 Kuhner tray 32/450 32 x 450 ml 800 x 420 Alu 1 1 12
87412 Kuhner tray 20/450 20 x 450 ml 500 x 420 Alu 1 1 10
87413 Kuhner tray 16/450 16 x 450 ml 420 x 420 Alu 1 1 10
87431 Infors Multitron tray 32/450 32 x 450 ml 850 x 470 Alu 1 1 12
87433 Infors Minitron tray 16/450 16 x 450 ml 480 x 420 Alu 1 1 10
87611 Kuhner tray 32/600 32 x 600 ml 800 x 420 Alu 1 1 10.2
87612 Kuhner tray 20/600 20 x 600 ml 500 x 420 Alu 1 1 7.0
87613 Kuhner tray 16/600 16 x 600 ml 420 x 420 Alu 1 1 6.5
87631 Infors Multitron tray 32/600 32 x 600 ml 850 x 470 Alu 1 1 10.7
87633 Infors Minitron tray 16/600 16 x 600 ml 480 x 420 Alu 1 1 7.0

Opening

87015 + 87017: 5 x openings: A = 0.4 mm, B = 0.6 mm, C = 1.0 mm, D = 1.25 mm, E = 1.5 mm

87050/87056: 5 x openings:  A = 0.4 mm, B = 0.6 mm, C = 1.0 mm, D = 1.5 mm, E = 2.0 mm
87450/87600: 10 x openings with size 4.0 mm each

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