TubeSpin® Bioreactor
TPP TubeSpin® Bioreactors have proven their advantages in large scale screening and optimisation processes of suspension cells. The optimization of the parameters, important for the production up-scaling, can be evaluated with small amounts maximising the number of parallel experiments at the same time. 

Features of the

  • TubeSpin® Bioreactor 15: working volume 1 - 15 ml
    • round or conical bottom
  • TubeSpin® Bioreactor 50: working volume 1 - 35 ml
    • conical bottom
  • TubeSpin® Bioreactor 450: working volume 1 - 300 ml (not yet launched)
    • conical bottom
  • TubeSpin® Bioreactor 600: working volume 1 - 400 ml
    • conical bottom
    • matching adapter plates for shakers available
  • filter screw cap with partly 5 different openings (A, B, C, D, E) above the gas permeable, sterile PTFE filter
  • steril gas exchange is guaranteed by the 0.22 µm filter membrane
  • tubes fit in a standard centrifuge rotors
Consumables for bioreactors:
  • replacement screw caps for large bioreactors
  • rack for bioreactor 450/600 ml
  • rack for bioreactor 15/50 ml
  • TPP adapterplates for Shaker from Kuhner or Infors, fit up to 8 x 4 tubes
 

 

 

"Dr. Shaker" offers advice on any issues concerning shaken bioreactors.

 

"Dr. Shaker" offers advice on any issues concerning shaken bioreactors. 

His recommendations for spin, throw and shaking speed can be downloaded here.

Good to know!
Dr. Shakers recommendations, tips and tricks:

 

 

From swirling of wine to bioreactors - the essence of orbital shaking

An interesting film from scientists at EPFL that have managed to model the shape of the wave created in a glass of wine while swirling it. They figured out that given parameters allow reproducing the exact wave form, whatever the size of the recipient. These finding are useful to better calibrate orbital shaking bioreactors for cell culture. See original scientific footage (source: youTube).

 

Water loss

  • If small culture volumes are incubated over a longer period of time, the loss of water influences the growth of cells.
  • By the closure of one or several openings above the gas permeable and sterile PTFE membrane, this water loss can be minimized.

Steril gas exchange is guaranteed through the 0.22 µm pore size PTFE filter membrane.

Downloads

Information on 87600

TypeProduct No.VersionVolume (ml)Dimensions
(mm)
MaterialMax
g Force
Qty / BagQty / Case
 87015 15 ml, conical 15 17.1 x 120 PP 15500 40 800
 87017 15 ml, round 15 17.1 x 120 PP 15500 40 800
 87050 50 ml, conical 50 30 x 115 PP 15500 20 180
 787050 50 ml, conical, with barcode 50 30 x 115 PP 15500 20 180
 87450 450 ml, conical 450 96 x 145 PP 3500 1 32
 87600 600 ml, conical 600 100 x 183 PP 3500 1 26
 99013 Rack for 87600 3 x 87600 366 x 146 x 70 PP 1 6
 99017 Rack for 15 / 50 ml tube 18 x 15 ml / 10 x 50 ml 209 x 98 x 62 PP 1 45
 87605 screw cap "solid" 450/600 70 x 21 PE -- 5 40
 87606 screw cap "filter" 450/600 70 x 21 PE -- 5 40
--- TPP Adapterplate --- --- --- --- ---
 87611 Adapterplate 32 Kuhner 8 x 4 800 x 420 Alu 1 1
 87612 Adapterplate 20 Kuhner 5 x 4 500 x 420 Alu 1 1
 87613 Adapterplate 16 Kuhner 4 x 4 420 x 420 Alu 1 1
 87631 Adapterplate 32 Infors Multitron 8 x 4 850 x 470 Alu 1 1
 87633 Adapterplate 16 Infors Minitron 4 x 4 480 x 420 Alu 1 1

Opening

87015 + 87017: 5 x openings: A = 0.4 mm, B = 0.6 mm, C = 1.0 mm, D = 1.25 mm, E = 1.5 mm

87050: 5 x openings:  A = 0.4 mm, B = 0.6 mm, C = 1.0 mm, D = 1.5 mm, E = 2.0 mm
87450/87600: 10 x openings with size 4.0 mm each